Orphaned at an early age, Peter Parker lived in Queens, New York with his beloved Aunt May ,Academy-Awards nominee Rosemary Harris, and Uncle Ben, Academy Awards winner Cliff Robertson. Peter leads the life of a normal student, working as a photographer at the Daily Bugle under the tutelage of publisher J. Jonah Jameson , pining after the beautiful Mary Jane Watson and hanging out with buddy Harry Osborn .
On a school trip, during which Peter and his classmates are given a science demonstration on spiders, Peter is bitten by a genetically altered spider. Soon after, he discovers that he has unusual powers: he is endowed with the strength and agility of a spider along with a keen, ESP-like "spider sense."