Charlie Wilson (Hanks) was a bachelor congressman from Texas who had a habit of showing up in hot tubs with strippers and cocaine. His “Good Time Charlie” exterior, however, masked an extraordinary mind, a deep sense of patriotism and a passion for the underdog, and in the early 1980s the underdog was Afghanistan—which had just been brutally invaded by the Russians.

Charlie's longtime friend and patron and sometime lover was Joanne Herring (Roberts), one of the wealthiest women in Texas and a virulent anti-communist. Believing the American response to the Russian invasion was anemic at best, she prods Charlie into doing more for the Mujahideen (Afghan freedom fighters).

Charlie's partner in this uphill endeavor is CIA Agent Gust Avrakotos (Hoffman), a blue-collar operative in a company of Ivy League blue bloods. Together, the three of them—Charlie, Joanne and Gust—travel the world to form unlikely alliances among the Pakistanis, Israelis, Egyptians, arms dealers, law makers and a belly dancer.

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